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In the pivotal SURMOUNT-1 trial, which tested tirzepatide for weight loss in 2,539 adults without diabetes, insomnia was not reported as a common or statistically significant adverse event

Sources: Serum Zinc Concentration in Patients with Alopecia Areata (2023) National Library of Medicine (accessed 12 September 2025) Stress-Related Hair Loss Among the General Population in Al Majma'ah, Saudi Arabia: A Cross-Sectional Study (2023) Cureus (accessed 12 September 2025) Telogen effluvium (2023) British Association of Dermatology (accessed 12 September 2025) Telogen effluvium (hair shedding) (2019) DermNet (accessed 12 September 2025) Telogen effluvium: Symptoms, treatment, and recovery (2024) Medical News Today (accessed 12 September 2025) Tirzepatide Once Weekly for the Treatment of Obesity (2022) New England Journal of Medicine (accessed 12 September 2025) The Role of Vitamins and Minerals in Hair Loss: A Review (2018) Dermatology and Therapy (accessed 12 September 2025) Treatment of insulin resistance with tirzepatide leading to improvement of hair loss (2024) American Academy of Dermatology (accessed 12 September 2025)

Quick Answer: Body aches are not listed as common side effects of tirzepatide in UK product information, though some patients report musculoskeletal discomfort during treatment

Even mild dehydration can precipitate acute kidney injury in patients with chronic kidney disease
Mounjaro, Zepbound and Tirzepatide: What Is the Difference

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