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Injecting too quickly can increase pressure in the tissue and cause more vascular damage, while a dull needle or one that hasn't been inserted at the correct angle may require multiple attempts

Consistent with these biological effects, data from a large population-based cohort in Taiwan showed that initiation of GLP-1RAs, compared with insulin, was associated with a significantly lower incidence of HCC (HR = 0.47, 95% CI: 0.360.61) (Yang et al., 2024)

Medication overuse headache - an under-diagnosed problem in shunted idiopathic intracranial hypertension patients

Understanding the fundamental differences between these medication classes is essential for making informed treatment decisions

Sometimes it delivers nothing at all

If nausea or abdominal discomfort is disrupting sleep, discuss with your GP whether: Dose escalation should be slowed to allow better tolerance Anti-emetic medication might be appropriate for managing nausea (only use medications prescribed or recommended by your healthcare provider) Dietary modifications could reduce gastrointestinal symptoms According to the SmPC, Wegovy can be administered at any time of day, with or without food