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Diabetologia 62:665675 Bergmann NC et al (2020) No acute effects of exogenous glucose-dependent insulinotropic polypeptide on energy intake, appetite, or energy expenditure when added to treatment with a long-acting glucagon-like peptide 1 receptor agonist in men with type 2 diabetes

Before semaglutide, I often found myself struggling with my weight, feeling confined to a small section of my closet

Contact your healthcare provider if you experience significant weight regain (more than 5% of lost weight), worsening blood glucose control, severe abdominal pain, or other concerning symptoms

It is the model behind it

Side effects and safety considerations Mounjaro is a dual GIP/GLP-1 receptor agonist which has known common and serious side effects

Trial #2 Compared tirzepatide with patients on metformin to semaglutide