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tirzepatide and iih Tirzepatide: A First-in-class Twincretin for the Management of Type 2 Diabetes Tirzepatide Trial for Idiopathic Intracranial
Description
During rapid weight loss, the body may undergo metabolic adaptationsometimes called "adaptive thermogenesis"where energy expenditure decreases beyond what would be expected from reduced body mass alone
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Slight adjustments up, even by 0.5 mg per week, can recapture the effect
Retrieved from Alyafei, A., Balfour, J., & Keyes, D

Limitations : As a case report with one patient (N=1 study), the findings are anecdotal and require corroboration through larger, controlled studies to establish broader applicability
