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10.1523/JNEUROSCI.5369-03.2004 J

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Techniques like ion-pairing reversed-phase liquid chromatography (IP-RPLC) are widely used to monitor peptide critical quality attributes (CQAs), with hyphenated LC-MS approaches playing a key role in enhancing sensitivity and selectivity, enabling quantification of low-level impurities

Niche-independent high-purity cultures of Lgr5+ intestinal stem cells and their progeny