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1 , nicotine caused a dose-dependent growth inhibition of a broad spectrum of our test organisms, some of which are known pathogens

however, the risk for malignant transformation proved to be low, which was confirmed by the clinical and pathological aspects of the lesion

Stronger pouches (10 mg+) may hit faster, which is why new users often start with lower strengths to gauge their tolerance

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Key to its acceptance is that there be no upper level for nicotine that is set so low as to effectively ban cigarettes (Schwartz and Kaufman, 2000)