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[Google Scholar] Hemodynamic and autonomic effects of smokeless tobacco in healthy young men

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Further well-known substances found in cigarette smoke are nicotine, polycyclic aromatic hydrocarbons, and cadmium as well as other metals and substances like benzene, formaldehyde, or tar [17, 19, 21, 42, 48, 75]

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The adverse effects of nicotine in the hepatic system include the upregulation of inflammatory cytokines, the development of secondary polycythemia, and blockage of proliferation and activation of apoptosis in lymphocytes