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E-cigarettes and asthma Chronic inflammation and airway hyperresponsiveness are key pathophysiological features of bronchial asthma, characterized by increased reactivity of the airways to non-specific stimuli, leading to airway smooth muscle contraction, increased airway resistance, and airflow limitation [65]

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"Use relieves stress and anxiety" Nicotine never fixed stress

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At the beginning of the study, the average participant would smoke about 20 cigarettes a day