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An assay measuring the abundance of H2AX in human bronchial epithelial cells can, therefore, be used to evaluate whether the extent of DNA double-strand breaks caused by the cMRTP aerosol is lower than that caused by cigarette smoke [47, 48]

Die Reaction nahm an Intensitt in den nchsten 2 bis 3 Stunden nur sehr wenig zu, wurde dann aber deutlich intensive, so dass erst etwa 4--5 Stunden nach Beginn des Versuches sich grssere Mengen freier Salicylsure in der Verdauungsflssigkeit fanden