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The medial habenula is enriched in 5*, 3*, 4* nAChRs, which have been shown to mediate nicotine aversion, drug-taking behavior, and/or withdrawal (96101)

Tsukada H, Miyasato K, Kakiuchi T, Nishiyama S, Harada N, Domino EF (2002)

The industry continues to use this tactic because of its impact on governments that are vulnerable to economic downturn and lack resources to curb illicit trade