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Although designed for a same goal, VC10 and RM20S have been shown to deliver significantly different deposited masses and nicotine concentrations for an identical puffing regimen [43]

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[35] [36] A 2025 study that analyzed data from the National Vital Statistics System (NVSS), the Behavioral Risk Factor Surveillance System (BRFSS), the National Health Interview Survey (NHIS), and the National Survey on Drug Use and Health (NSDUH) concluded that e-cigarettes had preserved 677,000 lifeyears from 2011 to 2019