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Type of study: meta-analysis Number of citations: 365 Year: 2012 Authors: C

Age and Sex Distribution in the Philippine Population (2020 Census of Population and Housing)

Kobayashi Y, Sakai C, Ishida T, Nagata M, Nakano Y, Ishida M

& Schroeder, S

In addition, the increased nicotinic receptors can also explain Tolerance , or the need to use more of the product containing nicotine to get the original effect

These changes are further elevated in lung cancers or pre-cancers when compared to normal lung tissue, supporting the idea that the epigenetic changes associated with smoking allow cells to grow more quickly, the study said