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Mitral annulus velocities were measured using pulsed Tissue Doppler by positioning a 5 mm-sample volume at the level of septal, lateral, inferior and anterior annulus, in accordance with current ASE recommendations [21]

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A survey from BMJ journals found that of the smoking population, nearly half smoked over 20 cigarettes per day

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I think thats not right with just these two numbers, we can compute the relative risk of the two groups