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Unfortunately, harmines substantial neurotoxic impacts in animal models prevented it from being developed clinically

[DOI] [PubMed] [Google Scholar] 2.Ng M, Freeman MK, Fleming TD, Robinson M, Dwyer-Lindgren L, et al

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Topical products include creams, balms, gels that are used primarily to reduce localized pain (muscle, nerve, inflammatory) or reduce skin irritation from conditions like eczema or psoriasis

According to the World Health Organization (WHO), tobacco cultivation and harvesting can expose farmers to nicotine and other harmful chemicals, leading to respiratory problems, skin diseases, and other health issues