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DNMT3A and DNMT3B are bona fide de novo methyltransferases that methylate DNA without a template (Tang et al., 2009)

A study in Bangladesh, for example, is currently looking at how teaching children about the dangers of passive smoking and encouraging them to talk to the adults in their family to persuade them to not smoke inside the home

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(A) The levels of miR-125a-5p in MLE-12 cells were measured by qRT-PCR (n = 3)

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Maternal smoking before or during pregnancy significantly increased the risk of six subtypes of birth congenital anomalies (i.e., congenital diaphragmatic hernia, gastroschisis, limb reduction defect, cleft lip with or without cleft palate, cleft palate alone, and hypospadias), even as low as 15 cigarettes per day