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Asthma, a chronic respiratory disorder, is aggravated by smoking and can result in recurrent episodes of wheezing, chest tightness, shortness of breath, and coughing

In September 2020, the FDA started reviewing premarket tobacco applications and has since issued marketing denial orders for 55,000 flavored ENDS products, on the grounds the applicants dont have sufficient evidence that the benefit to adult smokers outweighs the risk to youth

[Erratum, Nicotine Tob Res 2005;7:307.] [DOI] [PubMed] [Google Scholar] 29.Le Moal M, Koob GF

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Longer and/or denser filters generally have higher filtration efficiency, and the combined effects of increased filtration and increased ventilation dilute the smoke so it tastes weaker or milder and produces less harshness (the immediate burning/ scratching sensations in the mouth and throat) and irritation (the lingering tingling sensations in the throat and chest)

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