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PMID 31593518

For example, one study that examined current smoking status on the 36-item Short-Form Health Survey questionnaire (SF-36) found that differences were not large, being of the order of 0.20.5 standard deviation 22
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Later work demonstrated that the combined absence of the p53 target genes encoding the pro-apoptotic BH3-only proteins PUMA and NOXA (and to a lesser extent loss of PUMA alone) rendered lymphoid cells as resistant to DNA damage-inducing agents as loss of p53 itself [8, 9, 22]