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States like Missouri, which have lower cigarette taxes and weaker smoking bans, experienced much smaller declines in per capita alcohol consumption (2.44 gallons at the start of the study period to 2.42 gallons when the study period ended)

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CO prevents the maturation of dendritic cells and lowers the production of pro-inflammatory cytokines and the proliferation of effector T cells, whereas it stimulates the secretion of the anti-inflammatory cytokine IL-10 which may explain the beneficial effects in UC [51]

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