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Smoking a cigarette delivers nicotine rapidly to the pulmonary venous circulation, from which it moves quickly to the left ventricle of the heart and to the systemic arterial circulation and brain
Biochem Pharmacol 74(8):1112
You can always remove more if there is not enough airflow, but you cannot get back whatever you remove
J Biol Chem 2021;296:100397
While poor diet is often blamed for this condition, smoking can also be the primary cause
