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moderate certainty), but may result in little to no harm from other adverse events, such as hiccups, gastrointestinal disturbances, skin irritation from patches, throat irritation, or runny nose.43 Varenicline results in small harms from increases in nausea (32 RCTs, n = 14 963

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While the longitudinal study 17 and two cross-sectional studies 16,21 did not find any age-based differences, one cross-sectional study reported that younger cancer survivors had significantly higher odds of being current vapers compared to older cancer survivors 24