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However, the guidelines were released with a recommendation for further research to improve screening uptake and identify biomarkers that could more accurately detect people likely to benefit from screening

In the event of an emergency and/or a situation where the safety, care, and best interest of the participant is compromised by not knowing the treatment allocation, the QI or PI will contact the study pharmacy staff to initiate unblinding procedures

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The Smoke-Free Ontario Act, 2017, targets exposure to second-hand smoke and vapour in defined settings, and its motor-vehicle restrictions are limited primarily to situations involving minors

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