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Molecular alterations in basal cell carcinoma subtypes

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JNK targets p53 ubiquitination and degradation in nonstressed cells

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Defective p53 post-translational modification required for wild type p53 inactivation in malignant epithelial cells with mdm2 gene amplification

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[DOI] [PMC free article] [PubMed] [Google Scholar] 55.Lee P., Vousden K.H., Cheung E.C

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Double-stranded DNA

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Mouse xenograft models also demonstrate that ATO reactivates mutp53 to suppress tumors [144]

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