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And third, cigarette smoking prior to PET scanning and cognitive testing simulated real-world smoking in that participants smoked to satiety in an outdoor area, which was intended to enhance generalizability

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Secondary outcomes There was no clear evidence of a difference in post-intervention scores of heaviness of smoking (mean difference = 0.30, F (1,72) = 1.263, p = 0.27, motivation to stop smoking (mean difference = 0.46, F (1,72) = 2.012, p = 0.16) or autonomy over smoking (mean difference = 0.25, F (1,72) = 0.042, p = 0.84) between study arms with adjustment for the same measures taken at baseline (Table 2)