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These studies indicated that chewing nicotine gum results in maximum levels of nicotine in the blood, similarly as those observed during smoking (55, 56)

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Overview of the NIH PATH study The study analyzed data from 2,652 adults who had a history of substance use disorder and who had a change in their recovery status in the past 4 years
Dr Andrew Huberman, a Stanford University neuroscientists, likened the intense but transient rush that comes from inhaling an e-cigarette to smoking crack cocaine

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Their cause is a mystery -- it could be a reaction to a food or a minor trauma like biting the tongue