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A new study suggests otherwise smoking actually triggers stress

Cigarette smoke causes direct injury to airway cells (Decramer et al., 2012) and may hasten the aging of lungs, thus accelerating the progression of COPD (Kazuhiro & Barnes, 2009)

However it is also one of the most critiqued, even in the field of smoking cessation, where it was originally formulated

In this case, the authors suggest that the failure to achieve a therapeutic INR may be due to increased vitamin K exposure resulting from the patients chewing tobacco consumption