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Retrieved June 24, 2021

Spread : Soon after, it reached the Ottoman Empire, the Middle East, and other Islamic regions through trade routes

HMF has a sweet and floral scent, but the role of HMFCA in flavoring is not reported, since the substance itself is not very well-known

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They then used chemical antagonists to inactivate a specific nicotine receptor called alpha-7 in the aversion network, which reduced the effects of aversive nicotine on neural activity