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Low-Intensity Smoking Still Raises Major Cardiovascular Risks An extensive review of nearly two dozen long-term studies shows that people who smoke only a small number of cigarettes still face a much higher likelihood of heart disease and early death compared to those who have never smoked

[DOI] [PubMed] [Google Scholar] 94.Dresel S, et al

World Health Organization: 800

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Nicotine acts on cholinergic signaling mechanisms to directly modulate choroid plexus function