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Chemistry of Tobacco Smoke No less than 4000 irritating, suffocating, dissolving, inflammable, toxic, poisonous, carcinogenic gases and substances and even radioactive compounds (nickel, polonium, plutonium, etc.) have been identified in tobacco smoke

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Daniel McGehee and colleagues at the University of Chicago have shown that along with directly stimulating the brains reward system, nicotine also stimulates it indirectly by altering the balance of inputs from two types of neurons that help regulate its activity level

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Chemical composition of aerosol from an e-cigarette: A quantitative comparison with cigarette smoke