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They could demonstrate that nicotine exposure alters the function of monocyte-derived DCs, including (1) antigen uptake : no significant change was observed in macropinocytosis, but endocytic and phagocytic properties of immature DCs were reduced

The Major Brands All Owned by Big Tobacco Notice the pattern: Every major nicotine pouch brand is either owned by a tobacco giant (Philip Morris, BAT, Altria/Marlboro) or marketed by media personalities profiting from the product