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Although there has been a recent surge in global studies on oral microbiome, its dysbiosis, and its association with oral cancer and gut microbiome (Shillitoe, 2018), only a limited number of studies have been reported from the developing countries ( Methods Ethics Approval and Consent to Participate The study was reviewed and approved by the Institute Ethics Committee (IEC) of Indian Institute of Science Education and Research (IISER) Bhopal, India

While the exact cause of CHS is unknown, it is believed to be related to the bodys endocannabinoid system

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Reduce craving & withdrawal Increase successful quitting Lower healthcare and/or insurance costs Reduce youth initiation Why Restrict Smoking

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