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Animals of the db/db genotype are similarly obese, but in this case it is due to the lack of expression of leptin receptors and, as such, their weight is unaffected by exogenous leptin administration (Caro et al., 1996)
Edited by: Lepkowski JM, Tucker C, Brick JM, de Leeuw ED, Japec L, Lavrakas PJ, Link MW, Sangster RL
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