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Major Carcinogens in Tobacco The other major carcinogen in tobacco is NNK

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To investigate, the Austrian researchers limited their analysis to just over 22,000 men who had recently been treated surgically for prostate cancer, but were otherwise healthy

ChemPhysChem 16:978985 Lenoid S Chemissian v3.3, Khachatryan L et al (2003) Development of expanded and core kinetic models for the gas phase formation of dioxins from chlorinated phenols

Tupa, like other lobelias ( Lobelia inflata, Lobelia cardinalis, Lobelia chinensis or Lobelia siphilitica ) is rich in an alkaloid called lobeline