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When a cigarette is burnt, it releases thousands more chemicals in tobacco smoke

57 found that HBx proteins can induce GAS2 transcriptionally silenced in human hepatocytes, which can inhibit p53-dependent apoptosis and senescence to offset HBx protein-mediated oncogenesis
Transplacental transfer and biotransformation studies of nicotine in the human placental cotyledon perfused in vitro

doi: 10.1101/cshperspect.a000109

Lin CH, Shih CH, Chen BC

Mutant p53 cancers reprogram macrophages to tumor supporting macrophages via exosomal miR-1246
