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Description

In particular, metalloproteases 9 and 12, surfactant protein D, antimicrobial peptides (LL-37 and human defensin 2), and IL-1, IL-6, IL-8, and IL-17 have been found in higher quantities in the lungs of smokers with ongoing inflammation

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Methods We developed cigarette smoke exposure protocols exposing mice to environmental smoking for 10 days or 3 months to determine acute and chronic smoke exposure effects