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As mentioned previously, extract of CA efficiently enhanced memory and cognitive function in Alzheimers mouse models by activating antioxidant response pathway and releasing the burden of reactive oxygen species (ROS) over-production and protecting normal function of hippocampal mitochondria [8587]

Notably, UPR-induced autophagy is speculated to stimulate the production of exosomes and soluble inflammatory signals that are proinflammatory and promote autoimmunity (46)

Inflammatory cells, such as neutrophils and macrophages, are recruited during an inflammatory response

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