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Methionine is a sulfur-containing amino acid that serves as a methyl donor in one-carbon metabolism, supporting the synthesis of S-adenosylmethionine (SAMe), which regulates hepatic lipid export

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This is exacerbated by reduced levels of serotonin and noradrenaline within the spinal cord, principally affecting the descending antinociceptive pathways [129,130]

Magnetic resonance imaging revealed a large herniated disc at L4-L5

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