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Furthermore, in mice testicular tissue, pretreatment with L-carnitine can inhibit apoptosis related to genes such as FasL, implicated in programmed cell death, and Cyclin D2, involved in cell cycle regulation, and oncogenic transformation and differentiation which are activated following radiation

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Statins induce both mitochondrial oxidative stress and calcium-dependent permeability transition, which may lead to cell injury and death

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[18], [19] VPA has also been demonstrated to have neuroprotective properties on glutamate-induced excitotoxicity via up-regulation of alpha-synuclein and increases neurite outgrowth in vitro