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To verify that the newly found metabolic reaction links to glutathione metabolism, we next treated cells with buthionine sulfoximine (BSO), which is an inhibitor of gamma-glutamylcysteine synthetase (GCS) in glutathione metabolism pathway 28

Concise update on methodological approaches The DNPH method is the most common procedure for the routine quantification of total protein carbonyls from a biological sample and the results are broadly used as a general index of protein oxidation (Estvez 2011

The complexity of eicosanoid biosynthesis is layered in the dynamic expression and intracellular compartmentalization of the biosynthetic machinery that is time-, condition-, and cell type-dependent

Implications for dimer stability and comparison with endothelial nitric-oxide synthase

In recent decades, calcium channel blockers and modulators of mitochondrial dynamics, such as mitochondrial division inhibitor 1 (Mdivi-1) and the mitochondrial fusion promoter M1, have demonstrated cardioprotective and neuroprotective properties in various experimental models [129, 135, 136]

Brem, H., & Tomic-Canic, M
