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Methods: We have carried out a study enrolling 20 patients affected by SD to evaluate the effectiveness and tolerability of a new topical formulation in cream (hereinafter SEB) containing GSH-C4 0.4% in hyaluronic acid 0.25% a new synthetic glutathione derivate called INCI (butyroyl glutathione)-assigned by the Personal Care Council

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Renn, C, , Ramos Lopez, E, , Steimle-Grauer, SA, , Ziolkowski, P, , Pani, MA, , Luther, C, , Holzer, K, , Encke, A, , Wahl, RA, , Bechstein, WO, , Usadel, KH, , Hansmann, ML, , Badenhoop, K, 2004 Thyroid fetal male microchimerism in mothers with thyroid disorders: presence of Y-chromosomal immunofluorescence in thyroid infiltrating lymphocytes is more prevalent in Hashimoto's thyroiditis and Graves' disease than in follicular adenomas

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Inflammatory responses increase oxidative stress and oxygen free radicals, which impair GAG synthesis

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