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[DOI] [PMC free article] [PubMed] [Google Scholar] 77.Wang Y., Wu H., Dong N., Su X., Duan M., Wei Y., Wei J., Liu G., Peng Q., Zhao Y
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Researchers commonly use cobalamin preparations in analytical chemistry, assay development, and studies involving methylation and cellular cofactors

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18 Table 4 Time to Improvement of Abnormalities in Vitamin B12 Deficiency After Initiation of Treatment A 2005 Cochrane review involving 108 patients with vitamin B 12 deficiency found that high-dose oral replacement (1 mg to 2 mg per day) was as effective as parenteral administration for correcting anemia and neurologic symptoms
