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Collectively, these results suggest that hepatic FPN downregulation in MASLD may contribute to iron overload and associated metabolic disorders, establishing a potential mechanistic link between altered iron homeostasis and metabolic dysfunction (Figure 2K)

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Metabolic dysfunction and oxidative stress in epilepsy

Thus, ROS and autophagy interact closely with each other

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In observational studies, CKD and dialysis patients who received calcitriol or synthetic vitamin D analogs (active forms of vitamin D that do not require the kidney for activation) exhibited reduced cardiovascular and all-cause mortality (Zheng 2013)
