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indicated that flupirtine, a clinically available analgesic activating slow axonal K + channels in the A-fibers of peripheral nerve, alleviated the acute OIPN by suppressing axonal hyperexcitability (Sittl et al., 2010)

Li Y, Li Z, Grillo E, Desler C, Navarro C, Bohr VA, Berliocchi L, Rasmussen LJ

The HPLC was an Agilent 1290 (Agilent Technologies, Santa Clara, CA, USA), equipped with a fluorescence detector operating at excitation wavelengths of 405 and 488 nm, and emission wavelength of 499 nm

mitochondrial, SHMT2) catalyzes the transfer of the beta carbon of serine to tetrahydrofolate (THF) to form glycine and one-carbon units, 5,10-methylene-THF (Figure 1), which is critical for nucleotide synthesis
Eur J Haematol 86 (1): 38-46, 2011

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