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Exosomes can carry therapeutic substances such as small molecule drugs, nucleic acids (such as siRNA and miRNA) (Seyedaghamiri et al., 2023

This could theoretically lead to a deficiency syndrome where the body neutralizes its own sleep/stress regulatory factors, potentially causing autoimmunity or hypersensitivity reactions

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Lyophilization helps maintain material stability by reducing moisture exposure and supporting long-term storage, helping researchers achieve consistent experimental preparation
