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The avidity with which ET is retained in mammalian systems and toxicity associated with its depletion in response to stress and its dietary origin led us to propose that ET merits designation as a vitamin

Moreover, exposure of cancer cells to stimuli such as hypoxia, radiation and chemotherapy causes cell damages and leads to protein degradation, resulting in increased levels of TCA cycle intermediates and in an enhanced haem biosynthesis 49,50

Published online July 28, 2020

[DOI] [PMC free article] [PubMed] [Google Scholar] 75.Marso S.P., Bain S.C., Consoli A., Eliaschewitz F.G., Jdar E., Leiter L.A., Lingvay I., Rosenstock J., Seufert J., Warren M.L., et al

An oral supplement has to travel through your digestive tract, survive stomach acid, bind to a protein called intrinsic factor, and be absorbed in the small intestine
[DOI] [PubMed] [Google Scholar] Nishinaka T, Ichijo Y, Ito M, Kimura M, Katsuyama M, Iwata K, Miura T, Terada T, Yabe-Nishimura C
