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VEGF is the main angiogenic factor controlling vessel growth, vascular homeostasis, permeability, and vessel dilation

Results A counter-selection system was engineered in Saccharomyces cerevisiae based on the known feedback inhibition of gamma-glutamylcysteine synthetase (GSH1) gene expression, which is rate limiting for GSH synthesis: the GSH1 ORF and the counter-selectable marker GAP1 were expressed under control of the TEF1 and GSH-regulated GSH1 promoters, respectively

N-Acetyl-L-Cysteine (NAC) is an antioxidant amino acid and a precursor in the body to the endogenous antioxidant glutathione.* Glutathione is important for detoxification

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