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HMGCoA, 3-hydroxy-3-methylglutaryl coenzyme A reductase

Kononenko NL, Claen GA, Kuijpers M, Puchkov D, Maritzen T, Tempes A, et al

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Nasiri-Ansari N, Nikolopoulou C, Papoutsi K, Kyrou I, Mantzoros CS, Kyriakopoulos G, et al

However, more intensive studies are needed to gain a better understanding of the mechanisms of action ( The present study aimed to assess the potential therapeutic effects of PA on APAP-induced hepatotoxicity and the possible underlying mechanisms through its effects on CYP2E1 gene expression, serum and tissue iron load, oxidative stress and SIRT-1 expression