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This -globin gene variant was found to be mostly responsible for inhibiting HbS polymerization found in sickle cell disease, the 2 T87Q 2 tetramer has similar oxygen affinity as HbA and the T87Q variant can be used to track gene correction efficiency in clinical trials

Alteration of platelet aggregation by cigarette smoke and carbon monoxide
Proc Biochem 40:34743479

Nanoparticles for targeted brain drug delivery: What do we know

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