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However, we found that it is virtually fully oxidized, when expressed in the periplasm, suggesting that its engineered cysteine residues are completely oxidized by the oxidative folding machinery

Also, the conjugates showed good uptake by the Dox-resistant cell line (MDA-MB-435R), where Dox showed minimal uptake

2024 Jul 13];11(11)

Supplementary information Glossary Alloantigens Antigens from a genetically different individual of the same species that trigger an immune response in the recipient, such as donor-derived proteins in transplantation

It is derived from octanoic acid and is transported into the cells where it is rapidly reduced to dihydrolipoic acid (DHLA), the more bioactive form of alpha lipoic acid, which possesses the unique ability to neutralise free radicals

The idea is systemic rejuvenation: improving not just skin or hair, but overall cellular repair throughout the body