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Noticeable benefits like improved elasticity, reduced wrinkles, and smoother skin usually appear after 8-12 weeks, with maximum results around 16 weeks or more

Wallert J, Gustafson E, Held C, Madison G, Norlund F, Von Essen L, Olsson EMG (2018) Predicting adherence to internet-Delivered psychotherapy for symptoms of depression and anxiety after myocardial infarction: machine learning insights from the U-CARE heart randomized controlled trial

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