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Until the beginning of the 21st century, the idea of mitochondrial autophagy was initially termed as mitophagy to define the selective elimination of depolarized mitochondria in autophagosome (Scott and Klionsky, 1998

The 3 patients were moved from IM therapy to oral therapy but remained in the minimal compliance group as they did not meet indications for treatment based on the serum B12 values

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In a similar way, binding and facilitated uptake of 5-(3,4-dihydroxyphenyl)--valerolactone into human monocytes and a macrophage cell line were demonstrated (20)